Melatonin is a naturally occurring hormone that is produced by the pineal gland inside of the brain. There is increasing evidence that melatonin levels are related to migraine and cluster headaches. Synthetic melatonin is commonly used by people with sleeping disorders, such as insomnia, to help regulate their sleep cycles. Studies are currently under way to evaluate the efficacy of melatonin in the prevention and treatment of migraine headaches.
Although more research is required, early results are promising. In a study published in the August 2004 issue of Neurology, participants took just 3 mg of melatonin 30 minutes before bedtime for a period of 3 months. At the end of the study, 78% of participants reported a 50% decrease in headache frequency and 25% of participants reported no headaches at all during the study period.
If you are a migraine sufferer, then this may be an alternative therapy that is worth considering. Even though melatonin is available over the counter, you should always consult your doctor before beginning any new treatment.